Childhood depression and adult personality disorder -: Alternative pathways of continuity
Childhood depression and adult personality disorder -: Alternative pathways of continuity
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DOI：
10.1001/archpsyc.58.3.231
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发表时间：
2001-03-01
影响因子：
--
通讯作者：
Brook, JS
中科院分区：
文献类型：
--
作者：
Kasen, S;Cohen, P;Brook, JS
背景资料：本研究扩展了以前的发现的风险所造成的儿童期重性抑郁症和其他精神病理学特征，后来的人格障碍（PD）在随机抽样的551 youth.Methods：自我报告和母亲的报告被用来评估DSM-III-R（轴I和II）的精神疾病，平均年龄为12.7，15.2，和21.1岁。Logistic回归分析被用来研究独立的影响，在儿童或青少年抑郁症的10 PD在年轻adult.Results：依赖，反社会，被动攻击，和表演PD的几率增加了13，10，7，和3倍以上，分别给予先前的抑郁症。这些影响与年龄、性别、弱势社会经济地位、儿童虐待史、不完整的家庭状况、父母冲突、青少年期既存PD以及其他儿童期或青少年期轴I精神病理学特征（包括破坏性和焦虑性障碍）无关。此外，odds的偏执型和自恋PD增加了近6倍，反社会PD的几率增加了近5倍，以前的破坏性disorder，和偏执型PD的几率增加了4倍，以前的焦虑disorder.Conclusion：人格障碍可能代表的替代路径的方式，连续性的重性抑郁症和其他轴I障碍在整个儿童-成人过渡。
Background: This study extends previous findings of the risks posed by childhood major depressive disorder and other psychopathological features for later personality disorder (PD) in a random sample of 551 youths.Methods: Self-reports and mother reports were used to evaluate DSM-III-R (Axes I and II) psychiatric disorders at mean ages of 12.7, 15.2, and 21.1 years. Logistic regression was used to examine the independent effects of major depressive disorder in childhood or adolescence on 10 PDs in young adulthood.Results: Odds of dependent, antisocial, passive-aggressive, and histrionic PDs increased by more than 13, 10, 7, and 3 times, respectively, given prior major depressive disorder. Those effects were independent of age, sex, disadvantaged socioeconomic status, a history of child maltreatment, nonintact family status, parental conflict, preexisting PD in adolescence, and other childhood or adolescent Axis I psychopathological features, including disruptive and anxiety disorders. In addition, odds of schizoid and narcissistic PD increased by almost 6 times and odds of antisocial PD increased by almost 5 times given a prior disruptive disorder, and odds of paranoid PD increased by 4 times given a prior anxiety disorder.Conclusion: Personality disorders may represent alternative path ways of continuity for major depressive disorder and other Axis I disorders across the child-adult transition.