Tophaceous pseudogout of the temporomandibular joint: a series of 3 cases

Tophaceous pseudogout of the temporomandibular joint: a series of 3 cases
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DOI:
10.1016/j.oooo.2013.12.007
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发表时间:
2014-03-01
影响因子:
2.9
通讯作者:
El-Mofty, Samir K.
El-Mofty, Samir K.
中科院分区:
医学4区
文献类型:
--
作者:
Abdelsayed, Rafik A.;Said-Al-Naief, Nasser;El-Mofty, Samir K.

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目标。我们报告了3例颞下颌关节(TMJ)的假脱位。研究设计。3例患者,2男1女,年龄在60至75岁之间,表现为单侧颞下颌关节区疼痛肿胀,伴有开口受限。x线摄影和计算机断层摄影显示TMJ髁上区域不透明的肿块。3例患者术前临床印象为“肿瘤病变”。显微镜检查显示大量深亲碱性钙化沉积团块,在偏振光下表现出双折射,形态与焦磷酸钙二水合物沉积一致,在这些病例中被称为“白垩性假out”。假性关节脱位是一种罕见的良性关节病,其临床和影像学表现与颞下颌关节的肿瘤相似。因此,当TMJ在临床和影像学上出现“肿瘤样”病变时,建议在鉴别诊断时考虑白垩性假牙。
Objective. We report a series of 3 cases of tophaceous pseudogout of the temporomandibular joint (TMJ).Study design. Three patients, two men and one woman, ranging in age between 60 and 75 years, presented with unilateral painful swelling of the TMJ area associated with limitation of mouth opening.Results. Radiographic and computed tomographic images showed opaque masses in the supracondylar region of the TMJ. The preoperative clinical impression was a "neoplastic lesion" in the 3 cases. Microscopic examination revealed numerous deeply basophilic masses of calcified deposits, exhibiting birefringence under polarized light and morphologically consistent with calcium pyrophosphate dihydrate deposition, referred to in these cases as "tophaceous pseudogout."Conclusion. Tophaceous pseudogout is a rare benign arthropathy that presents with clinical and radiographic features mimicking neoplastic conditions of the TMJ. Therefore, it is recommended that tophaceous pseudogout be considered in the differential diagnosis when a TMJ is involved with "neoplasm-like" lesions clinically and radiographically.