Preterm birth: seven-year retrospective study in a single centre population
Preterm birth: seven-year retrospective study in a single centre population
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DOI：
10.1186/s13052-019-0643-9
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发表时间：
2019-04-11
影响因子：
3.6
通讯作者：
Triolo, Onofrio
中科院分区：
文献类型：
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作者：
Granese, Roberta;Gitto, Eloisa;Triolo, Onofrio
背景：早产是一个健康和社会问题，被认为是全球新生儿死亡的首要原因。它与较高的神经发育疾病发病率、感觉神经损伤和其他并发症相关。本研究的目的是描述早产的发生率以及与之相关的主要风险因素。
方法：我们在墨西拿G. 马尔蒂诺大学医院妇产科进行了一项单中心、观察性和回顾性队列研究。收集了2010年1月1日至2016年12月31日期间所有分娩孕妇的临床记录。
结果：在所考虑的7年中，我们的研究共纳入7954名孕妇。所有早产中，大多数是晚期早产婴儿（71.83%），26.45%是早产，1.72%是极早产。早产队列中有早产分娩史的比例更高（p < 0.0001），未婚者（p = 0.003）以及体重过轻或肥胖患者（p < 0.0001）的比例也更高。此外，早产与子宫异常（p < 0.0001）、阴道/泌尿系统感染（p = 0.02）、羊水过多/过少（p < 0.0001）、母体糖尿病（p = 0.004）、高血压（p < 0.0001）、宫颈长度短（p < 0.0001）有关。
结论：我们建议及时识别与早产相关的所有风险因素，以便立即实施适当的具体干预措施。
Background: Preterm birth is a health and social problem, considered the leading cause of neonatal mortality worldwide. It is associated with higher rates of neurodevelopmental morbidity, sensorineural impairments and other complications. The aim of the study was to describe the incidence and the major risk factors associated with preterm birth.Methods: We performed a single center, observational and retrospective Cohort study in the Division of Obstetrics and Gynaecology, University Hospital G. Martino, Messina. Clinical records of all pregnant women who delivered from 1st January 2010 to 31 of December 2016 were collected.Results: In the 7 years considered, a total of 7954 pregnant women were included in our study. The majority of all preterm births were due to infants born late preterm (71.83%), 26.45% were due to preterm and 1.72% to extremely preterm. The preterm cohort had a higher proportion of history of preterm delivery (p < 0.0001), and unmarried (p = 0.003) and underweight or obese patients (p < 0.0001). In addition, prematurity was associated with presence of uterine anomalies (p < 0.0001), vaginal/urinary infections (p = 0.02), poli/oligohydramnios (p < 0.0001), maternal diabetes (p = 0.004), hypertension (p < 0.0001), short cervical length (p < 0.0001).Conclusions: We suggest prompt identification of all risk factors associated with preterm birth to apply immediate and appropriate specific interventions.