INTERACTION OF DNA WITH A PORPHYRIN LIGAND - EVIDENCE FOR INTERCALATION
INTERACTION OF DNA WITH A PORPHYRIN LIGAND - EVIDENCE FOR INTERCALATION
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DOI：
10.1093/nar/6.9.3093
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发表时间：
1979-01-01
影响因子：
14.9
通讯作者：
DATTAGUPTA, N
中科院分区：
文献类型：
--
作者：
FIEL, RJ;HOWARD, JC;DATTAGUPTA, N
卟啉光敏剂meso-四（4-N-甲基-吡啶基）卟啉四高氯酸盐通过嵌入和外部静电缔合作用与小牛胸腺DNA结合。这是根据Scatchard分析、粘度测定、热变性和圆二色性等测量结果得出的结论。
The porphyrin photosensitizer, meso-Tetra(4-N-methyl-pyridyl)porphine tetraperchlorate binds to calf thymus DNA by intercalation and by external electrostatic association. This was concluded from the results of measurements involving Scatchard analysis, viscometry, thermal denaturation, and circular dichroism.