Difference in Tracer Delay-induced Effect among Deconvolution Algorithms in CT Perfusion Analysis: Quantitative Evaluation with Digital Phantoms
Difference in Tracer Delay-induced Effect among Deconvolution Algorithms in CT Perfusion Analysis: Quantitative Evaluation with Digital Phantoms
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DOI：
10.1148/radiol.2511080983
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发表时间：
2009-04-01
期刊：
影响因子：
19.7
通讯作者：
Shirato, Hiroki
中科院分区：
文献类型：
--
作者：
Kudo, Kohsuke;Sasaki, Makoto;Shirato, Hiroki
获得机构审查委员会批准和知情同意。其目的是通过使用从实际源数据创建的数字模型来评估用于计算机断层扫描（CT）灌注成像的各种去卷积算法的示踪剂延迟诱导效应的差异。三种方法的奇异值分解（SVD）进行了评估。对于标准SVD（sSVD），延迟引起脑血流量和平均通过时间的显着误差。相比之下，对于块循环SVD（bSVD），这些值几乎保持不变，而对于延迟校正SVD（dSVD），观察到轻度变化。bSVD在避免CT灌注成像中示踪剂延迟效应方面优于sSVD和dSVD，具有上级优势。(C)RSNA，2009年
Institutional review board approval and informed consent were obtained. The purpose was to evaluate the differences in tracer delay-induced effects of various deconvolution algorithms for computed tomographic (CT) perfusion imaging by using digital phantoms created from actual source data. Three methods of singular value decomposition (SVD) were evaluated. For standard SVD (sSVD), the delays induced significant errors in cerebral blood flow and mean transit time. In contrast, for block-circulant SVD (bSVD), these values remained virtually unchanged, whereas for delay-corrected SVD (dSVD), mild changes were observed. bSVD was superior to sSVD and dSVD for avoiding the tracer delay-induced effects in CT perfusion imaging. (C) RSNA, 2009