Maternal obesity is a potential source of error in mid-trimester ultrasound estimation of gestational age

Maternal obesity is a potential source of error in mid-trimester ultrasound estimation of gestational age
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DOI:
10.1002/uog.7502
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发表时间:
2010-01-01
影响因子:
7.1
通讯作者:
Kallen, K.
Kallen, K.
中科院分区:
医学1区
文献类型:
--
作者:
Simic, M.;Wahlin, I. A.;Kallen, K.

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目的 探讨孕产妇肥胖对妊娠超声测年可能的影响。 方法 使用瑞典医学出生登记处确定了 842 083 例单胎妊娠,其中根据末次月经 (EDD-LMP) 和妊娠早期超声检查 (EDD-US) 和孕妇体重指数 (BMI) 确定了预计分娩日期 (EDD)。超声检查后对日期进行了调整,负调整代表根据超声检查的怀孕时间比根据末次月经的怀孕时间短。根据出生年份、产妇年龄、产次和吸烟情况调整优势比 (OR)。 结果 EDD 推迟至少 7 天(EDD-LMP 和 EDD-US 之间的差异 = 30.0 kg/m(2),与 BMI 为 20.0-24.9 kg/m(2) 的女性相比,推迟 EDD 的风险显着更大。EDD 更常推迟 >= 14 天BMI >= 30 kg/m(2) 的女性与体重正常的女性相比,该风险相似(OR,1.65;95% CI,1.60-1.70)或 7-13 天(OR,1.45;95% CI,1.42-1.48)。在 BMI 25.0-29.9 kg/m(2) 的女性中观察到类似的风险,但较低。结论 高孕妇 BMI 会增加妊娠中期超声检查推迟 EDD 的风险。版权所有 (c) 2009 ISUOG 由 John Wiley & Sons, Ltd 出版。
Objectives To investigate the possible impact of maternal obesity on ultrasonographic dating of pregnancy.Methods The Swedish Medical Birth Registry was used to identify 842 083 singleton pregnancies for which the estimated date of deliver), (EDD) according to last menstrual period (EDD-LMP) and according to ultrasound examination (EDD-US) and maternal body mass index (BMI) in early pregnancy were known. Dates were adjusted following ultrasound examination, negative adjustment representing pregnancies that were shorter according to ultrasound examination than they were according to LMP. Odds ratios (OR) were adjusted for year of birth, maternal age, parity and smoking.Results The EDD was postponed at least 7 days (discrepancy between EDD-LMP and EDD-US of = 30.0 kg/m(2), the risk of postponed EDD was significantly greater compared with women with a BMI of 20.0-24.9 kg/m(2). The EDD was more often postponed >= 14 days (OR, 1.65; 95% CI, 1.60-1.70) or 7-13 days (OR, 1.45; 95% CI, 1.42-1.48) among women with a BMI >= 30 kg/m(2) than among women with normal weight. Similar risk was observed among women with a BMI of 25.0-29.9 kg/m(2), but was less pronounced.Conclusions High maternal BMI increases the risk of postponing the EDD at mid-trimester ultrasound examination. Copyright (c) 2009 ISUOG. Published by John Wiley & Sons, Ltd.