Right occipital transtentorial approach for a pineal malignant germ cell tumor.
Right occipital transtentorial approach for a pineal malignant germ cell tumor.
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DOI：
10.3171/2021.4.focvid2151
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发表时间：
2021-07
期刊：
影响因子：
--
通讯作者：
Bruce, Jeffrey N
中科院分区：
文献类型：
--
作者：
Gill, Brian J A;Higgins, Dominique M;Banu, Matei A;Argenziano, Michael G;Feldstein, Neil A;Bruce, Jeffrey N
在松果体区域发现的恶性病变中，生殖细胞肿瘤占53%，通常采用放射治疗和化疗相结合的治疗方法。颅内生殖细胞瘤的恶性体细胞转化极为罕见，仅在另外两种情况下报道。在这里，作者提出一例松果体卵黄囊肿瘤，在最佳的一线治疗失败后，发生了恶性体细胞转化为肠粘液腺癌，需要手术干预。本视频展示了枕部经额幕入路和安全的松果体区病变显微外科解剖技术的细微差别。视频可以在这里找到：https://stream.cadmore.media/r10.3171/2021.4.FOCVID2151。
Germ cell tumors account for up to 53% of the malignant lesions found in the pineal region and are typically managed with a combination of radiation therapy and chemotherapy. Malignant somatic transformation of intracranial germ cell tumors is exceedingly rare and has only been reported on two other occasions. Here the authors present the case of a pineal yolk sac tumor that failed optimum first-line treatment and underwent malignant somatic transformation to an enteric mucinous adenocarcinoma requiring surgical intervention. This video demonstrates the technical nuances of the occipital transtentorial approach and the safe microsurgical dissection of lesions within the pineal region. The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID2151.