Synthesis and Chiroptical Properties of Double-Helical (M)- and (P)-o-Oligophenylenes
Synthesis and Chiroptical Properties of Double-Helical (M)- and (P)-o-Oligophenylenes
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双螺旋 (M)- 和 (P)-邻低亚苯基的合成和手性光学性质
DOI：
10.1021/acs.orglett.5b02102
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发表时间：
2015-09-04
期刊：
影响因子：
5.2
通讯作者：
Wong, Henry N. C.
中科院分区：
文献类型：
--
作者：
Chen, Jing-Xing;Han, Jian-Wei;Wong, Henry N. C.
合成了具有6、8、10和12个苯环的光学纯低聚苯的所有M和P异构体，并对其进行了充分的表征。Suzuki交叉偶联反应在四苯类化合物的合成中是一种可行的策略，它与铜介导的氧化交叉偶联反应一起被用于寻求低聚苯类化合物。X射线衍射分析结合比旋光和圆二色谱明确地确定了这些低聚苯分子独特的共价双螺旋骨架。
All of the M and P isomers of optically pure oligophenylenes with 6, 8, 10, and 12 phenyl rings were synthesized and fully characterized. The Suzuki cross-coupling reaction has been revealed to be a viable strategy in the syntheses of tetraphenylene derivatives, which, together with the copper-mediated oxidative cross-coupling reaction, were employed in the quest for the oligophenylenes. X-ray diffraction analysis in combination with specific rotation and circular dichroism spectroscopy unambiguously identified the unique covalent double-helical frameworks of these oligophenylene molecules.