Using the Human Plasma PeptideAtlas to Study Human Plasma Proteins

Using the Human Plasma PeptideAtlas to Study Human Plasma Proteins
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DOI:
10.1007/978-1-61779-068-3_23
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发表时间:
2011-01-01
期刊:
SERUM/PLASMA PROTEOMICS: METHODS AND PROTOCOLS
影响因子:
--
通讯作者:
Aebersold, Ruedi
Aebersold, Ruedi
中科院分区:
其他
文献类型:
--
作者:
Farrah, Terry;Deutsch, Eric W.;Aebersold, Ruedi

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多肽图谱是一个可通过网络访问的LC-MS/MS猎枪蛋白质组学结果数据库,该数据库来自不同实验室进行的数百项实验,所有数据都通过统一的分析管道进行处理。总共包括91个关于人体血浆和Scrum的实验。使用PeptideAtlas网络界面,用户可以浏览和搜索人类血浆多肽图谱,以找到已识别的多肽和已识别的蛋白质,查看光谱,并选择蛋白质类型的多肽。用户可以很容易地查看支持信息,如染色体图谱、估计的丰度和序列比对。在这里,通过对血浆中细胞因子受体的图解探索,指导读者使用人类血浆肽图谱。
Peptide Atlas is a web-accessible database of LC-MS/MS shotgun proteomics results from hundreds of experiments conducted in diverse laboratories, with all data processed via a uniform analysis pipeline. A total of 91 experiments on human plasma and scrum are included. Using the PeptideAtlas web interface, users can browse and search the Human Plasma PeptideAtlas for identified peptides and identified proteins, view spectra, and select proteotypic peptides. Users can easily view supporting information such as chromosomal mapping, estimated abundances, and sequence alignments. Herein, the reader is instructed in the use of the Human Plasma PeptideAtlas through an illustrated exploration of cytokine receptors in plasma.