Multi-taper transfer function estimation for stimulation artifact removal from neural recordings.
Multi-taper transfer function estimation for stimulation artifact removal from neural recordings.
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用于从神经记录中去除刺激伪影的多锥度传递函数估计。
DOI：
10.1109/iembs.2008.4649777
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Gluckman,BruceJ
中科院分区：
文献类型：
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作者：
Chernyy,Nick;Schiff,StevenJ;Gluckman,BruceJ
同时刺激和记录神经组织的能力对于创建反馈控制系统至关重要。这种刺激产生额外的电位，如记录系统所见。该伪影可以通过刺激电流的线性传递函数来近似。传递函数的计算由于测量噪声和频谱估计中固有的偏差和方差而变得复杂。我们通过使用多锥度技术来减少偏差和方差。我们证明了使用这种传递函数作为一种方法，以消除刺激伪影的背景下，施加低频（100Hz）电场在长期仪表动物的神经调制。
The ability to simultaneously stimulate and record from neural tissue is paramount to the creation of a feedback-enabled control system. This stimulation creates additional electrical potential as seen by the recording system. This artifact can be approximated by a linear transfer function of the stimulus current. The computation of the transfer function is complicated by measurement noise and the bias and variance inherent in spectral estimation. We reduce bias and variance by using multi-taper techniques. We demonstrate the use of this transfer function as a method to remove stimulation artifact in the context of neural modulation with applied low-frequency (≪ 100Hz) electric fields in chronically instrumented animals.