A rhodium(I)-catalyzed formal allenic Alder ene reaction for the rapid and stereoselective assembly of cross-conjugated trienes
A rhodium(I)-catalyzed formal allenic Alder ene reaction for the rapid and stereoselective assembly of cross-conjugated trienes
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DOI：
10.1021/ja027588p
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发表时间：
2002-12-25
影响因子：
15
通讯作者：
You, LF
中科院分区：
文献类型：
--
作者：
Brummond, KM;Chen, HF;You, LF
发现了铑催化的联烯桤木烯反应制备交叉共轭三烯。的范围和局限性目前正在调查，并获得迄今为止的结果reportedon.This方法显示诱人的官能团相容性容忍终端和内部炔，羟基，磺酰胺，醚，和二酯基团。通过未取代的铱（I）催化的桤木−烯反应，已经在提高烯侧链的立体选择性方面取得了进展。
A rhodium(I)-catalyzed allenic Alder ene reaction to prepare cross-conjugated trienes has been discovered. The scope and limitations are currently being investigated, and the results obtained to date are reported on. This method shows enticing functional group compatibility by tolerating terminal and internal alkynes, hydroxyl, sulfonamide, ether, and diester groups. Progress has been made to increase the stereoselectivity of the olefinic side chain via an unprecendented iridium(I) catalyzed Alder−ene reaction.