Mitigation of excessive fatigue associated with functional electrical stimulation.
Mitigation of excessive fatigue associated with functional electrical stimulation.
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DOI：
10.1088/1741-2552/aade1c
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发表时间：
2018-12
影响因子：
4
通讯作者：
Fuglevand AJ
中科院分区：
文献类型：
--
作者：
Buckmire AJ;Arakeri TJ;Reinhard JP;Fuglevand AJ
使用功能性电刺激(FES)恢复瘫痪肢体的运动功能会受到与人工刺激相关的快速疲劳的破坏。通常，单电极被用来激活患有FES的肌肉。然而，由于肌肉神经的高度分布分支，单个电极可能不能激活供应肌肉的整个运动轴突阵列。因此，用多个电极刺激肌肉可以获得更大的肌肉体积，从而减少疲劳。因此，我们比较了使用一个或四个经皮肌内电极对人胫前肌(TA)进行反馈控制刺激(25赫兹)时，踝关节背屈在20%最大自愿力下所能维持的耐力时间。此外，我们测量了对供应TA的神经的直接刺激和自主收缩的反应的耐力时间。在所有涉及电刺激的治疗中，刺激部位近端的麻醉性神经阻滞被用来隔离刺激的效果并减轻不适。单电极刺激的耐受时间(84±19 S)明显短于4个电极的耐受时间(2 32±12 3 S)。神经刺激反应的耐力时间(787±201 S)与自主收缩时的耐力时间(896±272 S)无显著差异。因此，与FES相关的过度疲劳可能是由于传统的FES系统无法招募全部支配肌肉的运动轴突所致，可以使用多个电极或神经电极来缓解。
Restoration of motor function in paralyzed limbs using functional electrical stimulation (FES) is undermined by rapid fatigue associated with artificial stimulation. Typically, single electrodes are used to activate muscles with FES. However, due to the highly distributed branching of muscle nerves, a single electrode may not be able to activate the entire array of motor axons supplying a muscle. Therefore, stimulating muscle with multiple electrodes might enable access to a larger volume of muscle and thereby reduce fatigue. Accordingly, we compared the endurance times that ankle dorsiflexion could be sustained at 20% maximum voluntary force using feedback controlled stimulation (25 Hz) of human tibialis anterior (TA) using one or four percutaneous intramuscular electrodes. In addition, we measured endurance times in response to direct stimulation of the nerve supplying TA and during voluntary contraction. In all sessions involving electrical stimulation, an anesthetic nerve block proximal to the site of stimulation was used to isolate the effects of stimulation and alleviate discomfort. Endurance time associated with stimuli delivered by a single intramuscular electrode (84 ± 19 s) was significantly smaller than that elicited by four intramuscular electrodes (232 ± 123 s). Moreover, endurance time in response to nerve stimulation (787 ± 201 s) was not significantly different that that produced during voluntary contraction (896 ± 272 s). Therefore, excessive fatigue associated with FES is probably due to the inability of conventional FES systems to enlist the full complement of motor axons innervating muscle and can be mitigated using multiple electrodes or nerve-based electrodes.
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影响因子：
4.6
作者：
FANG, ZP;MORTIMER, JT
通讯作者：
MORTIMER, JT
影响因子：
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