Microdroplet fabrication of silver-agarose nanocomposite beads for SERS optical accumulation
Microdroplet fabrication of silver-agarose nanocomposite beads for SERS optical accumulation
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DOI:
10.1039/c0sm00601g
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发表时间:
2011-01-01
期刊:
影响因子:
3.4
通讯作者:
Abell, Chris
中科院分区:
文献类型:
--
作者:
Abalde-Cela, Sara;Auguie, Baptiste;Abell, Chris
Microdroplets have been used as reactors for the fabrication of agarose beads with high uniformity in shape and size, and densely loaded with silver ions, which were subsequently reduced into nanoparticles using hydrazine. The resulting nanocomposite beads not only display a high plasmonic activity, but can also trap/concentrate analytes, which can be identified by means of surface-enhanced Raman scattering (SERS) spectroscopy. The size of the beads is such that it allows the detection of a single bead under a conventional optical microscope, which is very useful to reduce the amount of material required for SERS detection.