Preventable hospital admissions related to medication (HARM): Cost analysis of the HARM study
Preventable hospital admissions related to medication (HARM): Cost analysis of the HARM study
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DOI：
10.1016/j.jval.2010.10.024
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发表时间：
2011-01-01
期刊：
影响因子：
4.5
通讯作者：
Postma, Maarten J.
中科院分区：
文献类型：
--
作者：
Leendertse, Anne J.;Van den Bemt, Patricia M. L. A.;Postma, Maarten J.
目的：药物不良事件（ADEs）可对患者造成严重伤害，并可导致住院甚至死亡。ADE不仅对患者及其亲属，而且对社会都是一种负担，并可能涉及高昂的费用。为了提供更多关于门诊患者可预防的药物不良事件的经济负担的信息，我们对药物相关住院（HARM）研究中收集的数据进行了成本研究。在本研究中，我们检查了与药物相关的住院频率、可预防性和风险因素。方法：通过将所有可预防住院的直接医疗成本和生产损失相加，计算与药物相关的可预防住院的平均费用。考虑到不同类型的医院结果：一个可预防药物相关的住院的平均医疗费用为（原文如此）5461。对于65岁以下的人来说，一次入院的平均生产损失成本为1 712美元。结合医疗成本和生产损失的成本导致的平均成本（原文如此）6009为一个，潜在的可预防的，与药物有关的住院治疗的所有年龄段。结论：潜在的可预防的住院治疗的费用与药物有关是相当大的。因此，预防ADE和住院的患者安全干预措施可能具有成本效益，甚至可以节省成本。版权所有（C）2011，国际药物经济学和结局研究学会（ISPOR）。爱思唯尔公司出版
Objective: Adverse drug events (ADEs) can cause serious harm to patients and can lead to hospitalization or even death. ADEs are a burden not only to patients and their relatives, but also to society and have the potential to involve high costs. To provide more information on the economic burden of preventable adverse drug events of outpatients, we performed a cost study on the data collected in the Hospital Admissions Related to Medication (HARM) study. In this study we examined the frequency, preventability, and risk factors for hospital admissions related to medication.Methods: The average costs for a preventable medication-related hospital admission were calculated by summing the direct medical costs and the production losses of all the preventable admissions, taking into account the different types of hospitals (academic and general) and the age of the admitted patients.Results: The average medical costs for one preventable medication-related hospital admission were (sic)5461. The average production loss costs for one admission were (sic)1712 for a person younger than 65 years of age. Combining the medical costs and the costs of production losses resulted in average costs of (sic)6009 for one, potentially preventable, medication-related hospital admission for all ages.Conclusions: The costs of potentially preventable hospital admissions related to medication are considerable. Therefore, patient safety interventions to prevent ADEs and hospital admissions may be cost-effective or even cost saving. Copyright (C) 2011, International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc.