miR-155 and miR-31 are differentially expressed in breast cancer patients and are correlated with the estrogen receptor and progesterone receptor status
miR-155 and miR-31 are differentially expressed in breast cancer patients and are correlated with the estrogen receptor and progesterone receptor status
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DOI：
10.3892/ol.2012.841
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发表时间：
2012-11-01
期刊：
影响因子：
2.9
通讯作者：
Liu, Zhenzhen
中科院分区：
文献类型：
--
作者：
Lu, Zhenduo;Ye, Yuping;Liu, Zhenzhen
本研究旨在检测67例浸润性导管内乳腺癌患者组织和血浆中microRNA（miR）-155和miR-31的水平及其与临床病理特征的相关性。使用定量实时PCR（qRT-PCR）分析，证实患者血浆中miR- 155和miR-31的水平分别是健康个体的6倍和5倍（P
The purpose of the present study was to determine the tissue and plasma levels of microRNA (miR)-155 and miR-31 in 67 patients with invasive intraductal breast cancer and their correlation with the clinicopathological characteristics. Using a quantitative real-time-PCR (qRT-PCR) assay, it was demonstrated that the plasma levels of miR- 155 and miR-31 in patients were 6- and 5-fold higher than those in healthy individuals, respectively (P