Health-related quality of life and antihypertensive medication adherence among older adults
Health-related quality of life and antihypertensive medication adherence among older adults
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DOI：
10.1093/ageing/afq040
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发表时间：
2010-07-01
期刊：
影响因子：
6.7
通讯作者：
Krousel-Wood, Marie A.
中科院分区：
文献类型：
--
作者：
Holt, Elizabeth Winter;Muntner, Paul;Krousel-Wood, Marie A.
方法：参与者是一项队列研究的一部分，该研究的老年人在管理式护理组织中登记并接受高血压治疗（n = 2，180）。使用兰德医学结局研究36项工具评估HRQOL的身体和精神成分总分（PCS和MCS）。结果：参与者的平均年龄为75.0 ± 5.6岁，69.3%为白色，58.5%为女性，14.1%的抗高血压药物依从性低。HRQOL评分低与老年人抗高血压药物依从性低水平相关。调整后的协变量，低PCS和MCS评分的1.33（95%CI 1.01，1.74）和2.26（95%CI 1.74，2.97）倍，分别有较低的抗高血压药物治疗依从性比PCS和MCS评分在前2个tertiels.Conclusions：低HRQOL可能是一个重要的障碍，以实现高的药物治疗依从性。
Methods: participants were part of a cohort study of older adults enrolled in a managed care organisation and treated for hypertension (n = 2,180). Physical and Mental Component Summary Scores (PCS and MCS) of HRQOL were assessed using the RAND Medical Outcomes Study 36-item tool. Adherence to antihypertensive medication was assessed with the eight-item Morisky Medication Adherence Scale.Results: the mean age of participants was 75.0 +/- 5.6 years, 69.3% were white, 58.5% were women and 14.1% had low antihypertensive medication adherence. Low HRQOL scores were associated with lower levels of antihypertensive medication adherence in older adults. After adjustment for covariates, those with low PCS and MCS scores were 1.33 (95% CI 1.01, 1.74) and 2.26 (95% CI 1.74, 2.97) times more likely, respectively, to have low antihypertensive medication adherence than those with PCS and MCS scores in the top 2 tertiles.Conclusions: low HRQOL may be an important barrier to achieving high medication adherence.