Using skin temperature gradients or skin heat flux measurements to determine thresholds of vasoconstriction and vasodilatation
Using skin temperature gradients or skin heat flux measurements to determine thresholds of vasoconstriction and vasodilatation
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DOI：
10.1007/s00421-002-0692-3
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发表时间：
2002-11-01
影响因子：
3
通讯作者：
Tipton, MJ
中科院分区：
文献类型：
--
作者：
House, JR;Tipton, MJ
前臂-指尖皮肤温差（Tsk-diff）用于指示血管紧张度，当Tsk-diff大于或等于4 ℃时，血管收缩被定义为已经发生（Sessler等，1987，1988 a，B）。本研究旨在确定Tsk-diff或指垫热通量（HF）是否可用于预测何时发生血管收缩和血管舒张。7名受试者（1名女性）坐在[平均（SD）] 40.7（0.8）℃的水中，直到他们的核心温度（T1）升高10 ℃，以确保血管舒张。然后[以0.6（0.1）℃.min（-1）的速率]冷却水，直到T-c降至低于试验前值0.5 ℃，引起血管收缩。然后将受试者在水中复温[41.2（1.0）℃]。皮肤血流量（SkBF）使用激光多普勒血流仪（LDF）在左手第二指垫上测量[作为另一个实验的一部分浸入10.4（1.4）℃的水中]，并在双手的第三指垫上使用红外体积描记法测量。在保持在空气中的右上肢上测量Tsk-diff和HF。当血管舒张时，受试者具有稳定的Tsk-diff和HE。在冷却期间，快速发作的血管收缩与HF和Tsk-diff的大梯度变化（拐点）同时发生。在两名受试者中，未达到最初的血管收缩定义（Tsk-diff大于或等于4 ℃），在其他5名受试者中，在血管收缩后31-51分钟达到。在复温期间，Tsk-diff和HF拐点较不准确地反映了血管舒张的开始，尽管有一个例外，它们在LDF变化的5分钟内。我们的结论是，Tsk-diff和HF拐点预测血管收缩准确，并优于Tsk-diff大于或等于4 ℃。
Forearm-fingertip skin temperature differentials (Tsk-diff) are used to indicate vasomotor tone, vasoconstriction defined as having occurred when Tsk-diff greater than or equal to4degreesC (Sessler et al. 1987, 1988a, b). This study was conducted to determine whether Tsk-diff or finger pad heat flux (HF) can be used to predict when vasoconstriction and vasodilatation occur. Seven subjects (one female) sat in water at [mean (SD)] 40.7 (0.8)degreesC until their core temperature (T,) increased by 1degreesC, ensuring vasodilatation. The water was then cooled [at a rate of 0.6 (0.1)degreesC.min(-1)] until T-c fell to 0.5degreesC below pretesting values, causing vasoconstriction. Subjects were then rewarmed in water [41.2 (1.0)degreesC]. Skin blood flow (SkBF) was measured using laser Doppler flowmetry (LDF) on the left second finger pad [immersed in water at 10.4 (1.4)degreesC as part of another experiment], and infrared plethysmography on the third finger pad of both hands. Tsk-diff and HF were measured on the right upper limb, which remained in air. When vasodilated, the subjects had a stable Tsk-diff and HE During cooling, rapid-onset vasoconstriction occurred coincidental with large gradient changes in HF and Tsk-diff (inflection points). In two subjects the original vasoconstriction definition (Tsk-diff greater than or equal to4degreesC) was not attained, in the other five this was achieved 31-51 min after vasoconstriction. During rewarming, the Tsk-diff and HF inflection points less accurately reflected the onset of vasodilatation, although with one exception they were within 5 min of the LDF changes. We conclude that Tsk-diff and HF inflection points predict vasoconstriction accurately, and better than Tsk-diff greater than or equal to4degreesC.