Analysis of cocaine-positive fatalities.
Analysis of cocaine-positive fatalities.
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可卡因阳性死亡人数分析。
DOI：
10.1520/jfs12610j
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发表时间：
1989
影响因子：
1.6
通讯作者：
R. Millman
中科院分区：
文献类型：
--
作者：
K. Tardiff;E. Gross;Jeffrey Wu;M. Stajíc;R. Millman
对纽约市11个月内死亡者的所有尸检和毒理学报告进行审查后发现，935人死于体内的可卡因。可卡因阳性死亡更可能发生在年轻的黑人、西班牙裔和男性人口中。除了可卡因及其代谢物外，在39%的死者中发现了海洛因和其他鸦片制剂，在33%的死者中发现了乙醇，只有2%的死者发现了巴比妥类药物和轻微的镇静剂。可卡因过量导致4%的死亡，海洛因和可卡因过量导致12%的死亡。暴力往往是死亡的原因。38%的人死于他杀，7%的人死于自杀，8%的人死于事故。特别令人感兴趣的是6人死于与可卡因直接相关的急性心脏事件，以及4例升主动脉夹层破裂和9例脑出血。这些人的尸检结果进行了描述，并讨论了可能的死亡机制。
A review of all autopsy and toxicology reports for persons dying in New York City in an 11-month period found 935 persons dying with cocaine in their bodies. Cocaine-positive fatalities were more likely in the young black and Hispanic and male population. In addition to cocaine and its metabolites, heroin and other opiates were found in 39% of persons and ethanol in 33% and barbiturates and minor tranquilizers in only 2% of the deceased. Cocaine overdose was responsible for 4% of the deaths and overdose with heroin and cocaine for 12% of the deaths. Violence was often the cause of death. Thirty-eight percent died of homicide, seven percent of suicide, and eight percent from accidents. Of particular interest were 6 persons who died of acute cardiac events directly related to cocaine as well as 4 cases of ruptured dissections of the ascending aorta, and 9 cases of cerebral hemorrhage. Autopsy findings for these individuals are described, and possible mechanisms of death are discussed.