Plasma volume expansion in early pregnancy
Plasma volume expansion in early pregnancy
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DOI：
10.1016/s0029-7844(00)01222-9
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发表时间：
2001-05-01
影响因子：
7.2
通讯作者：
Badger, GJ
中科院分区：
文献类型：
--
作者：
Bernstein, IM;Ziegler, W;Badger, GJ
目的：确定妊娠早期血浆容量扩张的时间进程。我们采用伊文思蓝染料稀释法前瞻性地测量了月经期间的血浆容量（周期第2-3天），卵泡（周期第9-10天）和黄体期（周期日尿促黄体生成激素[LH]峰加9-10）的月经周期和三个额外的时间点（LH峰+16天，LH峰+28天和LH峰+70天）。在38个月经周期期间检查21名受试者以建立基线月经周期数据。10名受试者在月经周期研究的1年内受孕。所有10例妊娠都是可行的，并达到了妊娠晚期。分析采用重复测量方差分析，P
Objective: To determine the time course of plasma volume expansion in early pregnancy.Methods: We prospectively measured plasma volume by Evens blue dye dilution during the menstrual (cycle day 2-3), follicular (cycle day 9-10), and luteal phases (cycle day urinary leutinizing hormone [LH] surge plus 9-10) of the menstrual cycle and at three additional time points (LH surge + 16 days, LH surge + 28 days, and LH surge + 70 days) in women achieving pregnancy. Twenty-one subjects were examined during 38 menstrual cycles to establish baseline menstrual cycle data. Ten subjects conceived within 1 year of menstrual cycle studies. All ten pregnancies were viable and reached the third trimester. Analyses used repeated-measures analysis of variance with P