The influence of neurocognitive impairment on HIV treatment outcomes among drug-involved people living with HIV/AIDS.
The influence of neurocognitive impairment on HIV treatment outcomes among drug-involved people living with HIV/AIDS.
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DOI：
10.1080/09540121.2011.608794
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发表时间：
2012
期刊：
影响因子：
1.7
通讯作者：
Potrepka J
中科院分区：
文献类型：
--
作者：
Ezeabogu I;Copenhaver MM;Potrepka J
迄今为止的研究结果表明，在社区环境中向感染艾滋病毒的注射吸毒者提供简短的行为风险降低/药物依从性小组干预是可行的。 HIV 感染和药物滥用可导致神经认知损伤，这与干预措施的制定直接相关，因为大量 HIV/艾滋病感染者有药物滥用史，能够成功参与行为干预通常需要相对较高水平的认知表现。本研究的目的是评估从基线到干预后在药物依从性、性行为和药物风险行为结果方面的信息、动机和行为技能的变化是否可以通过针对感染艾滋病毒的吸毒者进行简短的 4 节艾滋病毒整体健康干预（3H+）后的认知障碍来预测。研究发现动机的变化与某些神经认知表现领域之间存在显着关联。研究结果表明，专门定制此类行为干预措施以适应认知障碍可能会有所帮助。
Findings to date indicate that it is feasible to deliver a brief behavioral risk reduction/medication adherence group intervention to HIV-infected IDUs in a community-based setting. HIV infection and substance abuse can result in neurocognitive impairment and this is directly relevant to intervention development because a significant number of people living with HIV/AIDS have a positive history of substance abuse and being able to successfully participate in behavioral interventions often requires a relatively high level of cognitive performance. The aim of the current study was to evaluate if changes in information, motivation and behavior skills with respect to medication adherence, sex- and drug-risk behavior outcomes from baseline to post-intervention is predicted by cognitive impairment following the brief 4-session Holistic Health for HIV intervention for HIV-infected Drug Users (3H+). Significant associations were found between change in motivation and certain neurocognitive performance domains. Findings suggest that it may be helpful to specifically tailor such behavioral interventions to accommodate cognitive impairment.
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DOI：
10.1017/s1355617704101021
发表时间：
2004-01-01
影响因子：
2.6
作者：
Rippeth, JD;Heaton, RK;Grant, I
通讯作者：
Grant, I
影响因子：
1.7
作者：
Chander G;Himelhoch S;Fleishman JA;Hellinger J;Gaist P;Moore RD;Gebo KA
通讯作者：
Gebo KA
影响因子：
9.9
作者：
Hinkin, CH;Castellon, SA;Stefaniak, M
通讯作者：
Stefaniak, M
影响因子：
2.8
作者：
Copenhaver, M;Avants, SK;Margolin, A
通讯作者：
Margolin, A
影响因子：
3.5
作者：
Aydin, K.;Kircan, S.;Balaban, E.
通讯作者：
Balaban, E.