Surface current density mapping for identification of gastric slow wave propagation.

Surface current density mapping for identification of gastric slow wave propagation.
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DOI:
10.1109/tbme.2009.2021576
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发表时间:
2009-08
期刊:
IEEE transactions on bio-medical engineering
影响因子:
--
通讯作者:
Pullan AJ
Pullan AJ
中科院分区:
其他
文献类型:
--
作者:
Bradshaw LA;Cheng LK;Richards WO;Pullan AJ

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胃磁图无创记录胃电慢波的临床相关参数。除了慢波频率,胃慢波传播速度是胃组织健康状态的潜在有用的临床指标,但它是一个难以确定的参数,从非侵入性生物电或生物磁测量。我们提出了一种方法来计算表面电流密度(SCD)从多通道magnetogastrogram记录,允许计算的胃慢波的传播速度。一个移动的偶极子源模型与假设以及现实的生物磁力计参数表明,虽然一个相对稀疏的阵列的磁力计传感器是足以计算一个单一的平均传播速度,更详细的信息,传播速度的空间变化需要更高密度的磁力计阵列。最后,该方法进行了验证,同时在猪受试者的MGG和血清EMG测量。
The magnetogastrogram records clinically relevant parameters of the electrical slow wave of the stomach noninvasively. Besides slow wave frequency, gastric slow wave propagation velocity is a potentially useful clinical indicator of the state of health of gastric tissue, but it is a difficult parameter to determine from noninvasive bioelectric or biomagnetic measurements. We present a method for computing the surface current density (SCD) from multichannel magnetogastrogram recordings that allows computation of the propagation velocity of the gastric slow wave. A moving dipole source model with hypothetical as well as realistic biomagnetometer parameters demonstrates that while a relatively sparse array of magnetometer sensors is sufficient to compute a single average propagation velocity, more detailed information about spatial variations in propagation velocity requires higher density magnetometer arrays. Finally, the method is validated with simultaneous MGG and serosal EMG measurements in a porcine subject.