Electrospun DNA nanofibers

Electrospun DNA nanofibers
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DOI:
10.1116/1.2801886
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发表时间:
2007-11-01
影响因子:
1.4
通讯作者:
Craighead, Harold G.
Craighead, Harold G.
中科院分区:
工程技术4区
文献类型:
--
作者:
Bellan, Leon M.;Strychalski, Elizabeth A.;Craighead, Harold G.

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作者将荧光标记的DNA分子电纺成直径约为27 nm的纳米纤维。他们能够通过荧光显微镜、扫描电子显微镜和原子力显微镜对纳米纤维进行成像。纤维被沉积在预先形成图案的特征上,如电极和沟槽,允许将来测量和操纵DNA纳米纤维。作为这种测量的一个例子,他们使用原子力显微镜来测量单个DNA链的杨氏模量。(c)2007年美国真空学会。
The authors have electrospun fluorescently labeled DNA molecules into nanofibers with diameters of approximately 27 nm. They were able to image the nanofibers via fluorescence microscopy, scanning electron microscopy, and atomic force microscopy. Fibers were deposited over prepatterned features such as electrodes and trenches, allowing future measurement and manipulation of the DNA nanofibers. As an example of such a measurement, they have used an atomic force microscope to measure the Young's modulus of a single DNA nanofiber. (c) 2007 American Vacuum Society.