Excessive Exercise and Immunity: The J-Shaped Curve
Excessive Exercise and Immunity: The J-Shaped Curve
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DOI：
10.1007/978-1-4614-8884-2_24
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发表时间：
2013-08-29
期刊：
影响因子：
--
通讯作者：
Tacón AM
中科院分区：
文献类型：
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作者：
Chamorro-Viña C;Fernandez-del-Valle M;Tacón AM
运动调节免疫系统固有的和特定的手臂，具有明显的强度依赖性反应。这种反应可能受到性别差异和其他因素的影响，包括年龄、营养状况和整体心理压力水平。运动免疫学是研究这一领域的领域。在20世纪90年代，尼曼博士提出了有争议的“j形假说”来描述运动强度与患上呼吸道感染（URTI）风险之间的关系。这一假设表明，适度运动比久坐不动更能提高免疫功能，而高强度运动则会抑制免疫系统。然而，在j曲线的研究中存在一些方法学上的问题，这使得关于中等强度和高强度运动对尿路感染发病率的作用的证据更多的是轶事而不是证据。本章将介绍这些限制。
Exercise modulates the innate and specific arms of the immune system with a marked intensity-dependent response. This response might be influenced by sex differences and other factors including age, nutrition status, and overall level of psychological stress. Exercise immunology is the field that studies this area. In the 1990s, Dr. Nieman formulated the controversial “J-shaped hypothesis” to describe the relationship between exercise intensity and the risk of acquiring upper respiratory tract infections (URTI). This hypothesis suggests that moderate exercise has the ability to improve immune function above sedentary levels while high intensity exercise depresses the immune system. However, some methodological problems exist in studies of the J-curve which makes evidence more anecdotal than evidence-based regarding the role of moderate and intense exercise in the incidence of URTI. These limitations are presented in the chapter.