GOTreePlus: an interactive gene ontology browser
GOTreePlus: an interactive gene ontology browser
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DOI：
10.1093/bioinformatics/btn068
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发表时间：
2008-04-01
期刊：
影响因子：
5.8
通讯作者：
Seo, Jinwook
中科院分区：
文献类型：
--
作者：
Lee, Bongshin;Brown, Kristy;Seo, Jinwook
我们开发了一个名为GOTreePlus的交互式基因本体（GO）浏览器，它将注释信息叠加在GO结构上。它可以通过GO结构中重要GO术语的交互式可视化来促进重要GO术语的识别。交互式饼图总结了所选GO术语的注释分布，为用户提供了其实验结果的简洁上下文敏感概述。我们使用视网膜色素上皮细胞分化获得的蛋白质组分析数据集测试了我们的GOTreePlus，其中399种蛋白质被定量。
We developed an interactive gene ontology (GO) browser named GOTreePlus that superimposes annotation information over GO structures. It can facilitate the identification of important GO terms through interactive visualization of them in the GO structure. The interactive pie chart summarizing an annotation distribution for a selected GO term provides users with a succinct context-sensitive overview of their experimental results. We tested our GOTreePlus using a proteome profiling dataset obtained on differentiation of retinal pigment epithelial cells where 399 proteins were quantified.