High bandwidth force estimation for optical tweezers
High bandwidth force estimation for optical tweezers
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DOI：
10.1063/1.3116621
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发表时间：
2009-04-13
影响因子：
4
通讯作者：
Salapaka, Murti V.
中科院分区：
文献类型：
--
作者：
Sehgal, Hullas;Aggarwal, Tanuj;Salapaka, Murti V.
A prevalent mode of optical tweezers involves position clamping that regulates a constant position of a trapped bead. Traditional schemes employ the measured bead position in the open loop or the control signal in the position-clamp mode as an estimate of external force on the trapped bead. This article shows that traditional methods introduce fundamental limitations on bandwidth of the external force estimation. A method is presented that leads to an order of magnitude increase in the bandwidth of the external force estimation. Furthermore, a comprehensive modeling paradigm is introduced that facilitates estimation of forces on the bead.
