Influenza: The Once and Future Pandemic

Influenza: The Once and Future Pandemic
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DOI:
10.1177/00333549101250s305
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发表时间:
2010-04-01
影响因子:
3.3
通讯作者:
Morens, David M.
Morens, David M.
中科院分区:
医学4区
文献类型:
--
作者:
Taubenberger, Jeffery K.;Morens, David M.

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甲型流感病毒感染大量温血动物,包括野鸟、家禽、猪、马和人类。流感病毒可以转换宿主,在新宿主中形成新的谱系。其中最重要的事件是人类中出现抗原性新型甲型流感病毒,导致大流行。流感大流行已有至少 500 年的报道,大流行之间的间隔平均约为 40 年。
Influenza A viruses infect large numbers of warm-blooded animals, including wild birds, domestic birds, pigs, horses, and humans. Influenza viruses can switch hosts to form new lineages in novel hosts. The most significant of these events is the emergence of antigenically novel influenza A viruses in humans, leading to pandemics. Influenza pandemics have been reported for at least 500 years, with inter-pandemic intervals averaging approximately 40 years.