Reverse Remodeling and the Risk of Ventricular Tachyarrhythmias in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy)
Reverse Remodeling and the Risk of Ventricular Tachyarrhythmias in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy)
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DOI：
10.1016/j.jacc.2010.12.041
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发表时间：
2011-06-14
影响因子：
24
通讯作者：
Goldenberg, Ilan
中科院分区：
文献类型：
--
作者：
Barsheshet, Alon;Wang, Paul J.;Goldenberg, Ilan
目的评价心脏复律治疗（CRT）的超声心动图反应与随后发生室性快速性心律失常（VTA）的风险之间的关系。背景目前关于CRT对VTA风险影响的数据有限且相互矛盾。方法首次适当植入心律转复除颤器（ICD）治疗VTA的风险比较了CRT除颤器（CRT-D）治疗的高和低超声心动图应答者（定义为≥ 25%，
Objectives We aimed to evaluate the relationship between echocardiographic response to cardiac resynchronization therapy (CRT) and the risk of subsequent ventricular tachyarrhythmias (VTAs).Background Current data regarding the effect of CRT on the risk of VTA are limited and conflicting.Methods The risk of a first appropriate implantable cardioverter-defibrillator (ICD) therapy for VTA (including ventricular tachycardia, ventricular fibrillation, and ventricular flutter) was compared between high-and low-echocardiographic responders to CRT defibrillator (CRT-D) therapy (defined as >= 25% and