METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AT BOSTON CITY HOSPITAL - BACTERIOLOGIC AND EPIDEMIOLOGIC OBSERVATIONS
METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AT BOSTON CITY HOSPITAL - BACTERIOLOGIC AND EPIDEMIOLOGIC OBSERVATIONS
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DOI：
10.1056/nejm196808292790901
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发表时间：
1968-01-01
影响因子：
158.5
通讯作者：
FINLAND, M
中科院分区：
文献类型：
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作者：
BARRETT, FF;MCGEHEE, RF;FINLAND, M
从18例患者中检出耐甲氧西林金黄色葡萄球菌22株；其中21株噬菌体不可分型，对其他青霉素和头孢菌素耐甲氧西林，其特征与先前报道的耐甲氧西林菌株相似。这些葡萄球菌是从42个医院病房中的7个病房的患者中分离出来的。18名患者中有15名是在医院感染的。22株分离株中有13株来自12例肺部重复感染患者的痰液，4株来自2例导管相关性尿路感染患者的尿液。在一次病房暴发期间发现了患者间感染传播的证据，涉及4例临床病例和一名作为鼻咽带菌者的护士。
Twenty-two isolates of methicillin-resistantStaphylococcus aureuswere obtained from 18 patients; 21 of the strains were phage nontypable, exhibited methicillin resistance to other penicillins and cephalosporins tested, and had characteristics similar to those of previously reported methicillin-resistant strains.These staphylococci were isolated from patients on seven of the 42 hospital wards. Fifteen of the 18 patients acquired their infection in the hospital. Thirteen of the 22 isolates were from the sputum of 12 patients with pulmonary superinfection, and four from the urine of two patients with catheter-associated urinary-tract infections. Evidence of patient-to-patient spread of infection was found during a ward outbreak involving four clinical cases and a nurse who was a nasopharyngeal carrier.