Combined fMRI and MRI movie in the evaluation of articulation in subjects with and without cleft lip and palate
Combined fMRI and MRI movie in the evaluation of articulation in subjects with and without cleft lip and palate
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DOI：
10.1597/07-070
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发表时间：
2008-05-01
期刊：
影响因子：
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通讯作者：
Moriyama, Keiji
中科院分区：
文献类型：
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作者：
Sato-Wakabayashi, Michiru;Inoue-Arai, Maristela Sayuri;Moriyama, Keiji
目的：探讨功能性磁共振成像(FMRI)和MRI电影在评价唇腭裂(CLP)患者关节功能中的应用。设计：采用功能磁共振成像(FMRI)和MRI电影技术，对双唇唇腭裂(CLP)患者和非CLP志愿者的双侧唇腭裂(UCLP)和双侧唇腭裂(BCLP)受试者和12名非CLP受试者的中枢前回、丘脑和小脑进行脑激活和关节的动态运动检测。相比之下，UCLP受试者在两次抽动过程中激活的区域相似，而BCLP受试者激活的区域不同，尤其是在膜抽动期间。UCLP受试者关节的动态运动与非CLP受试者相当，但与BCLP受试者不同。结论：这两种MRI检查方法可以从中枢和外周角度评价CLP患者的关节功能。
Objective: This study was undertaken to explore the application of functional magnetic resonance imaging (fMRI) and MRI movies in the evaluation of articulatory function in subjects with and without cleft lip and palate (CLP).Design: The authors examined brain activation and the dynamic movement of articulators during bilabial and velar plosives using fMRI and MRI movies.Subjects: Two subjects, one with unilateral cleft lip and palate (UCLP) and one with bilateral cleft lip and palate (BCLP), and 12 non-CLP volunteers.Results: Activation foci were found in the precentral gyrus, thalamus, and cerebellum in non-CLP volunteers. In comparison, similar regions were activated in the UCLP subject during both plosives, whereas the regions activated in the BCLP subject were different, particularly during the velar plosive. The dynamic movement of articulators in the UCLP subject was comparable to that in a non-CLP volunteer but different from that in the BCLP subject.Conclusions: The results suggest that these two MRI modalities may be a promising evaluation methodology for articulatory function in CLP from central and peripheral perspectives.