Harnessing Ontologies for Argument-Based Decision-Making in Breast Cancer
Harnessing Ontologies for Argument-Based Decision-Making in Breast Cancer
复制标题
利用本体论进行乳腺癌基于论证的决策
DOI：
10.1109/ictai.2007.110
复制
发表时间：
2007
期刊：
影响因子：
--
通讯作者：
A. Hunter
中科院分区：
文献类型：
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作者：
Matthew Williams;A. Hunter
我们介绍了一种新的基于本体论的论证框架（OAF），链接基于逻辑的论证形式主义和描述逻辑本体论。我们展示了如何这两个形式主义可以紧密耦合，通过观察一些简单的限制，并提供了功能不提供任何形式主义单独。我们的工作是在一个大型的案例研究中进行评估的决策在乳腺癌的治疗选择，其中规则是从已发表的临床试验的结果，我们提出了一个小的子集，以证明该系统的使用。我们发现OAF提供了五个优点：（1）促进多个作者之间共享定义的清晰使用;（2）使我们能够将本体中的术语和规则与特定领域文献中的术语和规则匹配;（3）在临床试验结构和我们的规则结构之间提供紧密配合;（4）与现有方法相比，在规则库的大小上提供显著的经济效益;（5）使我们能够利用本体论和论证方法的发展。我们还证明，即使是一个有限的语言，如我们的是足以捕捉足够的信息，以产生的论点，是有用的临床实践。一个早期的原型实现是可用的。
We introduce a novel Ontology-based Argumentation Framework (OAF) that links a logic-based argumentation formalism and description logic ontologies. We show how these two formalisms can be tightly coupled by observing a few simple restrictions, and provides features not available in either formalism alone. Our work is evaluated in a large case study on decision-making in treatment choice in breast cancer, where rules are developed from the results of published clinical trials, and we present a small subset of this to demonstrate the use of the system. We show that OAF provides five advantages: (1) facilitating the clear use of shared definitions between multiple authors; (2) enabling us to match terms in the ontology and rules with those in the specific domain literature; (3) providing a close fit between structure of clinical trials and the structure of our rules; (4) delivering significant economies in the size of the rule-base compared to existing approaches; (5) allowing us take advantage of developments in both ontological and argumentative approaches. We also demonstrate that even a restricted language such as ours is sufficient to capture enough information to generate arguments that are useful for clinical practice. An early prototype implementation is available.