Percutaneous cardiopulmonary support in critical patients needing coronary interventions with stents

Percutaneous cardiopulmonary support in critical patients needing coronary interventions with stents
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需要支架冠脉介入治疗的危重患者的经皮心肺支持

DOI:
10.1002/ccd.10340
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发表时间:
2002
影响因子:
2.3
通讯作者:
Marcos Rodríguez
Marcos Rodríguez
中科院分区:
医学3区
文献类型:
--
作者:
J. Suárez de Lezo;M. Pan;A. Medina;D. Pavlovic;M. Romero;J. Segura;M. Ruiz;S. Ojeda;J. Muñoz;Marcos Rodríguez

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经皮心肺支持(CPS)已被证明是接受经皮球囊血管成形术的高危冠状动脉患者的一种有价值的技术。自1994年5月以来,我们在92例患者中联合使用CPS和冠状动脉支架血运重建术。在其中68例中,CPS被用作预防性手术(第1组);在其余24例中,CPS被用作紧急手术,以稳定甚至复苏急性心肌梗死和循环衰竭患者,以便尝试紧急经皮冠状动脉支架治疗(第2组)。第1组66例患者(97%)获得了一期成功。1例患者死亡,另1例患者发生心肌梗死。在28 ± 19个月的随访后,第1组的20例患者(30%)发生了重大不良心脏事件。其余46例患者(68%)仍存活,并具有持续的临床获益。在第2组中,总是实现再灌注和支架治疗。然而,14例患者发生了院内死亡。第2组的5例患者在随访时(47 ± 20个月)发生了重大不良事件。9名患者(38%)目前仍处于功能分级I-II级。经皮CPS为高危患者和急性心肌梗死和心力衰竭患者实现支架冠状动脉血运重建提供了安全条件。对幸存者的长期随访显示,大多数患者持续获益。导管介入2002;57:467-475。© 2002 Wiley利斯公司
Percutaneous cardiopulmonary support (CPS) has proven to be a technique of value in high‐risk coronary patients undergoing percutaneous balloon angioplasty. Since May 1994, we have combined the use of CPS and coronary stent revascularization in 92 patients. In 68 of them, the CPS was used as a prophylactic procedure (group 1); in the remaining 24, the CPS was used as an emergency procedure to stabilize and even resuscitate patients with acute myocardial infarction and circulatory collapse, in order to attempt urgent percutaneous coronary stent treatment (group 2). Primary success was achieved in 66 patients from group 1 (97%). One patient died and another had a myocardial infarction. After 28 ± 19 months of follow‐up, 20 patients (30%) from group 1 had a major adverse cardiac event. The remaining 46 patients (68%) are alive, with persistent clinical benefit. In group 2, reperfusion and stent treatment was always achieved. However, 14 patients had an in‐hospital death. Five patients from group 2 had a major adverse event at follow‐up (47 ± 20 months). Nine patients (38%) remain at present in functional class I–II. Percutaneous CPS provides safe conditions to accomplish stent coronary revascularization in high‐risk patients and those with acute myocardial infarction and failing heart. Long‐term follow‐up of survivors shows persistent benefit in most patients. Cathet Cardiovasc Intervent 2002;57:467–475. © 2002 Wiley‐Liss, Inc.