Environmental stimuli affecting expression of the Ysa type three secretion locus.

Environmental stimuli affecting expression of the Ysa type three secretion locus.
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环境刺激影响 Ysa 型三分泌位点的表达。

DOI:
10.1007/978-0-387-72124-8_18
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发表时间:
2007
影响因子:
--
通讯作者:
Miller,VirginiaL
Miller,VirginiaL
中科院分区:
医学4区
文献类型:
--
作者:
Mildiner-Earley,Shirly;Walker,KimberlyA;Miller,VirginiaL

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Yersinia enterocoliticahas two type III secretion systems (TTSS): The well characterized Ysc-Yop system and the relatively uncharacterized Ysa-Ysp system. Detection of Ysps in culture supernatants has only been observedin vitrowhen cultures are grown at low temperature (26°C) and in high salt (290mM NaCl). Previous reports demonstrated that expression from theysaEpromoter was activated by high salt. In this study, we report a new environmental stimulus forysagene expression; in the presence of high salt, growth on solid surface stimulates expression 7-fold compared to growth in high salt broth. These new data indicate that, in the presence of salt, solid surface is an extremely robust signal for the Ysa system.
DOI: 10.1126/science.285.5435.1920
发表时间: 1999-09-17
期刊: SCIENCE
影响因子: 56.9
作者:
Orth, K;Palmer, LE;Dixon, JE
通讯作者: Dixon, JE