Impact of Laser-Processed X'tal Cube Detectors on PET Imaging in a One-Pair Prototype System
Impact of Laser-Processed X'tal Cube Detectors on PET Imaging in a One-Pair Prototype System
复制标题
一对原型系统中激光加工 Xtal 立方体探测器对 PET 成像的影响
DOI：
10.1109/tns.2013.2280631
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发表时间：
2013
影响因子：
1.8
通讯作者：
T. Yamaya
中科院分区：
文献类型：
--
作者：
E. Yoshida;Y. Hirano;H. Tashima;N. Inadama;F. Nishikido;T. Moriya;T. Omura;Mitsuo Watanabe;H. Murayama;T. Yamaya
X立方是我们最初的PET探测器，它正在开发中，以实现各向同性3D定位检测。X形立方体是基于一个三维分割的晶体块，其所有表面都覆盖着光电探测器。在此之前，我们成功地构建了一个通过激光加工分割的晶体块，而不是我们最初的粘合晶体片段的方法，并且我们开发了一个X'tal立方体，其中包含激光加工的2毫米长的3D方形网格。在本文中，我们将激光加工扩展到长度为1mm的三维方形网格。1毫米晶体的体积是2毫米晶体体积的1/8。我们还使用新开发的一对原型系统来模拟环形扫描仪来评估成像分辨率性能，而我们之前的报告仅限于单个探测器的开发和评估。特别是，我们比较了1毫米X立方探测器和2毫米X立方探测器。单对原型系统由两个X形立方体、两个旋转工作台和一个192通道数据采集系统组成。每个X向立方体由18 × 18 × 18 mm3的LYSO立方晶体块组成，其中通过内部激光加工制成间距为1 mm的三维网格。将多像素光子计数器的4 × 4阵列光学耦合到晶体块的每个表面。自动控制探测器位置，模拟直径为14.6 cm的环形PET。收集所有假定的探测器位置的数据，然后得到正弦图。采用滤波后的反投影法重建数据。在视场（FOV）上，2 mm X向立方体的平均空间分辨率为1.9 mm。另一方面，1 mm X向立方体在视场上的平均空间分辨率为1.3 mm FWHM。在假设点源为1.0 mm FWHM的高斯函数的情况下，通过反卷积，我们估计了2 mm X'tal立方体和1 mm X'tal立方体的平均空间分辨率分别为1.6 mm FWHM和0.83 mm FWHM。与2毫米X立方相比，1毫米X立方的平均空间分辨率提高了约48%。总之，我们证实了X立方在均匀和高分辨率成像方面的潜力。
The X'tal cube is our original PET detector, which is being developed to achieve isotropic 3D positioning detectability. The X'tal cube is based on a 3D segmented crystal block for which all surfaces are covered with photo-detectors. Previously, instead of our initial approach of gluing segmented pieces of crystals, we successfully constructed a crystal block segmented by laser processing, and we developed the X'tal cube with the laser-processed 3D square grids of 2 mm length. In this paper, we extend the laser processing to 3D square grids of 1 mm length. The volume of a 1-mm crystal segment is 1/8 of that of a 2-mm crystal segment. We also evaluate imaging resolution performance with a newly developed one-pair prototype system to simulate a ring-type scanner, while our previous reports were limited to development and evaluation of a single detector. In particular, we compare 1-mm X'tal cube detectors to 2-mm X'tal cube detectors. The one-pair prototype system consisted of two X'tal cubes, two rotating stages, and a 192-channel data acquisition system. Each X'tal cube consisted of the LYSO cubic crystal block of 18 × 18 × 18 mm3 in which the 3D grids of 1 mm pitch were fabricated by internal laser processing. The 4 × 4 arrays of multi pixel photon counters were optically coupled to each surface of the crystal block. The detector positions were automatically controlled to simulate a ring-type PET with a 14.6 cm diameter. Data were collected for all assumed detector positions and then a sinogram was obtained. The data were reconstructed using filtered backprojection. The average spatial resolution of the 2-mm X'tal cube was 1.9 mm full width at half maximum (FWHM) over the field-of-view (FOV). On the other hand, the average spatial resolution of the 1-mm X'tal cube was 1.3 mm FWHM over the FOV. By applying deconvolution with the assumption that the point source was a Gaussian function of 1.0 mm FWHM, we estimated the average spatial resolution of the 2-mm X'tal cube and the 1-mm X'tal cube as 1.6 mm FWHM and 0.83 mm FWHM, respectively. The average spatial resolution of the 1-mm X'tal cube was improved approximately 48% compared to the 2-mm X'tal cube. In conclusion, we confirmed the potential of the X'tal cube for uniform and high resolution imaging.
DOI：
10.1016/j.nima.2010.11.092
发表时间：
2011-08-21
期刊：
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment
影响因子：
--
作者：
Moses WW
通讯作者：
Moses WW