High-resolution diffusion MRI.

High-resolution diffusion MRI.
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高分辨率扩散磁共振成像。

DOI:
10.1109/iembs.2007.4352286
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发表时间:
2007
期刊:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
影响因子:
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通讯作者:
Liang,Zhi-Pei
Liang,Zhi-Pei
中科院分区:
--
文献类型:
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作者:
Haldar,JustinP;Liang,Zhi-Pei

文献摘要

相似文献

本文提出了一种磁共振成像方法,可以提供高分辨率的图像表征水在生物组织中的扩散。这些图像包含有关组织微观结构的信息,从而提供了监测生理变化的有用手段。该方法克服了长期存在的问题,有限的信号-噪声比与扩散MRI通过使用惩罚最大似然重建。在小鼠大脑上进行的实验说明了该技术能够阐明使用其他非侵入性方法不可见的高分辨率结构细节。
This paper presents a magnetic resonance imaging method that can provide high-resolution images characterizing water diffusion in biological tissues. These images contain information about tissue microstructure, thereby providing a useful means to monitor physiological changes. The proposed method overcomes the long-standing problem of limited signal- to-noise ratio with diffusion MRI by using penalized maximum-likelihood reconstruction. Experiments performed on a mouse brain illustrate the ability of the technique to elucidate high resolution structural detail that would not be visible using other non-invasive approaches.