Artificial organelle: ATP synthesis from cellular mimetic polymersomes
Artificial organelle: ATP synthesis from cellular mimetic polymersomes
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DOI：
10.1021/nl051896e
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发表时间：
2005-12-01
期刊：
影响因子：
10.8
通讯作者：
Montemagno, CD
中科院分区：
文献类型：
--
作者：
Choi, HJ;Montemagno, CD
A complex cellular process was reconstructed using a multiprotein polymersome system. ATP has been produced by coupled reactions between bacteriorhodopsin, a light-driven transmembrane proton pump, and F(0)F(1)-ATP synthase motor protein, reconstituted in polymersomes. This indicates that ATP synthase maintained its ATP synthesis and therefore its motor activity in the artificial membranes. This hybrid proteopolymersome will have wide application in a number of fields ranging from the in vitro investigation of cellular metabolism to the synthesis of functional "smart" materials.
