Prognostic value of heart rate reserve is additive to coronary flow velocity reserve during dipyridamole stress echocardiography
Prognostic value of heart rate reserve is additive to coronary flow velocity reserve during dipyridamole stress echocardiography
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DOI：
10.1016/j.acvd.2020.01.005
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发表时间：
2020-04-01
影响因子：
3
通讯作者：
Picano, Eugenio
中科院分区：
文献类型：
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作者：
Cortigiani, Lauro;Ciampi, Quirino;Picano, Eugenio
背景- 在潘生丁负荷超声心动图（SE）中，心率储备（HRR）减弱是心脏自主神经功能障碍的一个不利体征。- 探讨HRR和冠状动脉血流储备（CFVR）对预后的意义。- 研究组包括2149例疑似（n=1280）或已知（n=869）冠状动脉疾病患者（1236例男性;平均年龄66 ± 12岁），在双嘧达莫SE（0.84 mg/kg，6 min）期间无可诱导的局部室壁运动异常（RWMA）。我们用脉冲多普勒评估左前降支的CFVR，即充血峰与基础舒张期峰值流速的比值（异常值
Background. - During dipyridamole stress echocardiography (SE), a blunted heart rate reserve (HRR) is a prognostically unfavourable sign of cardiac autonomic dysfunction.Aim. - To assess the prognostic meaning of HRR and coronary flow velocity reserve (CFVR).Methods. - The study group comprised 2149 patients (1236 men; mean age 66 +/- 12 years) with suspected (n=1280) or known (n=869) coronary artery disease and without inducible regional wall motion abnormalities (RWMA) during dipyridamole SE (0.84 mg/kg in 6 min). We assessed CFVR of the left anterior descending artery with pulsed-wave Doppler as the ratio between hyperaemic peak and basal peak diastolic flow velocities (abnormal value