The effectiveness of behavioral intervention for reduction of nausea and vomiting in children and adolescents receiving chemotherapy.
The effectiveness of behavioral intervention for reduction of nausea and vomiting in children and adolescents receiving chemotherapy.
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行为干预对减少接受化疗的儿童和青少年恶心和呕吐的有效性。
DOI：
10.1200/jco.1984.2.6.683
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
P. Zeltzer
中科院分区：
文献类型：
--
作者：
L. Zeltzer;S. Lebaron;P. Zeltzer
51名6-17岁的儿童在每个化疗过程中对恶心、呕吐的严重程度以及化疗困扰他们的程度进行了评估。16名患者没有症状，另外16名患者的剂量不恒定，因此无法评估匹配的疗程。在两个匹配疗程的基线测量后，其余19名患者被随机分配在另外两个匹配疗程中接受催眠或支持性咨询。在一半的患者中评估了无干预的额外疗程。在干预前，症状没有明显减轻。然而，催眠和支持性咨询的干预与恶心、呕吐的显著减少以及这些症状困扰患者的程度相关（所有p均小于0.001）。此外，在终止干预后，症状评分仍显着低于基线。这些数据表明，儿童化疗相关的恶心和呕吐可以通过行为干预来减少，并且在干预停止后保持减少。
Fifty-one children 6-17 years of age rated the severity of nausea, vomiting, and the extent to which chemotherapy bothered them during each course of chemotherapy. Sixteen patients had no symptoms and the doses administered to 16 others were not constant so that matched courses could not be assessed. After baseline measurement of two matched courses, the remaining 19 patients were randomized to receive hypnosis or supportive counseling during two more matched courses. An additional course with no intervention was assessed in half of the patients. No significant reduction of symptoms was demonstrated prior to intervention. However, intervention with both hypnosis and supportive counseling was associated with significant reductions in nausea, vomiting, and the extent to which these symptoms bothered patients (all p less than 0.001). Also, after termination of intervention, symptom ratings remained significantly lower than baseline. The data indicate that chemotherapy-related nausea and emesis in children can be reduced with behavioral intervention and that reductions are maintained after intervention has been discontinued.
放松训练和引导意象在减少癌症化疗厌恶情绪方面的功效。
影响因子：
5.9
作者：
Lyles,JN;Burish,TG;Krozely,MG;Oldham,RK
通讯作者：
Oldham,RK
化疗患者预期恶心和呕吐的患病率和相关性。
DOI：
--
发表时间：
1982
期刊：
Journal of the National Cancer Institute
影响因子：
--
作者：
Morrow,GR
通讯作者：
Morrow,GR