Respiratory mechanics and breathing pattern during and following maximal exercise.
Respiratory mechanics and breathing pattern during and following maximal exercise.
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最大运动期间和之后的呼吸力学和呼吸模式。
DOI：
10.1152/jappl.1984.57.6.1773
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
G. Kivinen
中科院分区：
文献类型：
--
作者：
M. Younes;G. Kivinen
我们在7名正常受试者中寻找最大运动时肺弹性回缩和吸气肌疲劳变化的证据。食管压力，流量和容量进行了测量，在自主呼吸的周期运动水平增加到最大。总肺容量（TLC）确定在休息和运动终止前立即使用N2冲洗技术。每隔1分钟测量一次最大吸气压和吸气量。计算运动终止前即刻自主呼吸的呼吸肌瞬时动态压（Pmus）的时间过程。TLC体积和TLC时的肺弹性回缩在运动结束时与休息时相同。运动终止时的最大静态吸气压没有降低。然而，在5名受试者中，运动结束时自主呼吸的平均Pmus超过最大吸气压力的15%。我们的结论是，肺弹性回缩是不变的，即使在最大的运动，而吸气肌肉操作在一个潜在的疲劳范围内，在最大的运动过程中观察到的高水平的通气没有保持足够的时间，导致机械疲劳。
We looked for evidence of changes in lung elastic recoil and of inspiratory muscle fatigue at maximal exercise in seven normal subjects. Esophageal pressure, flow, and volume were measured during spontaneous breathing at increasing levels of cycle exercise to maximum. Total lung capacity (TLC) was determined at rest and immediately before exercise termination using a N2-washout technique. Maximal inspiratory pressure and inspiratory capacity were measured at 1-min intervals. The time course of instantaneous dynamic pressure of respiratory muscles (Pmus) was calculated for the spontaneous breaths immediately preceding exercise termination. TLC volume and lung elastic recoil at TLC were the same at the end of exercise as at rest. Maximum static inspiratory pressures at exercise termination were not reduced. However, mean Pmus of spontaneous breaths at end exercise exceeded 15% of maximum inspiratory pressure in five of the subjects. We conclude that lung elastic recoil is unchanged even at maximal exercise and that, while inspiratory muscles operate within a potentially fatiguing range, the high levels of ventilation observed during maximal exercise are not maintained for a sufficient time to result in mechanical fatigue.