Ectopic bone formation and aging.
Ectopic bone formation and aging.
复制标题
异位骨形成和衰老。
DOI：
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发表时间：
1981
影响因子：
4.2
通讯作者：
E. Schneider
中科院分区：
文献类型：
--
作者：
J. Irving;S. LeBolt;E. Schneider
将从相同品系大鼠制备的脱钙骨粉植入6周龄、6月龄和2岁Wistar品系雌性大鼠。软骨和骨形成的包裹性存款。定期取出沉积物并进行组织学研究和45Ca给药后研究。6周龄大鼠膜内骨形成时间为14天，2岁大鼠膜内骨形成时间为23天。该种植体系统可为研究骨生成下降或随年龄增长发生的低骨形成率的机制提供模型。
Six-week-old, 6-month-old, and 2-year-old female rats of the Wistar strain were implanted with decalcified bone powder prepared from rats of the same strain. An encapsulated deposit of cartilage and bone formed. The deposits were removed at intervals and studied histologically and after administration of 45Ca. Intramembranous bone formed in 14 days in the 6-week-old animals, but was not seen until the 23rd day in the 2-year-old rats. This implant system may provide a model for the study of the mechanisms for the decline of osteogenesis, or the low bone formation rate which occurs with aging.