SIMAGE: simulation of DNA-microarray gene expression data.
SIMAGE: simulation of DNA-microarray gene expression data.
复制标题
DOI:
10.1186/1471-2105-7-205
复制
发表时间:
2006-04-13
影响因子:
3
通讯作者:
van Hijum SA
中科院分区:
文献类型:
--
作者:
Albers CJ;Jansen RC;Kok J;Kuipers OP;van Hijum SA
Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-processing and processing methods for best analysis of a given DNA microarray experiment, (iii) educating students, lab-workers and other researchers by making them aware of the many factors influencing DNA microarray experiments. Our model has multiple layers of factors influencing the experiment. The relative influence of such factors can differ significantly between labs, experiments within labs, etc. Therefore, we have added a module to roughly estimate their parameters from a given data set. This guarantees that our simulated data mimics real data as closely as possible. We introduce a model for the simulation of dual-dye cDNA-microarray data closely resembling real data and coin the model and its software implementation "SIMAGE" which stands for simulation of microarray gene expression data. The software is freely accessible at: .
登录
查看更多内容
影响因子:
4.8
作者:
den Hengst, CD;van Hijum, SAFT;Kuipers, OP
通讯作者:
Kuipers, OP
影响因子:
4.8
作者:
Piper, MDW;Daran-Lapujade, P;Pronk, JT
通讯作者:
Pronk, JT
影响因子:
--
作者:
Wolkenhauer, O;Möller-Levet, C;Sanchez-Cabo, F
通讯作者:
Sanchez-Cabo, F
影响因子:
4.4
作者:
van Hijum SA;de Jong A;Baerends RJ;Karsens HA;Kramer NE;Larsen R;den Hengst CD;Albers CJ;Kok J;Kuipers OP
通讯作者:
Kuipers OP
影响因子:
5.8
作者:
Martin-Magniette, ML;Aubert, J;Daudin, JJ
通讯作者:
Daudin, JJ