Longitudinal Case Series of Staphylococcus aureus Colonization and Infection in Two Cohorts of Rural Iowans.
Longitudinal Case Series of Staphylococcus aureus Colonization and Infection in Two Cohorts of Rural Iowans.
复制标题
爱荷华州农村两个群体中金黄色葡萄球菌定植和感染的纵向病例系列。
DOI：
10.1089/mdr.2017.0124
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Thapaliya,Dipendra
中科院分区：
文献类型：
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作者：
Smith,TaraC;Hellwig,EmilyJ;Wardyn,ShyloE;Kates,AshleyE;Thapaliya,Dipendra
目的：研究社区金黄色葡萄球菌定植与两个队列Iowans.Design：队列研究中的病例系列，参与者：从Keokuk农村健康研究，农业健康研究和爱荷华州选民登记中选出的爱荷华州农村居民。结果：我们在爱荷华州的两个队列中研究了这种关系，共11例S。aureusSSTI，其样品可用。11例个体中有7例（63.6%）在基线时在鼻子（3/7，42.9%）或鼻子和喉咙（57.1%）中定植。结论：金黄色葡萄球菌每年引起数百万皮肤和软组织感染。虽然殖民与S。由于金黄色葡萄球菌是感染的常见先兆，许多调查定植和感染之间联系的研究都是在临床环境中进行的，特别是在城市医院。我们的研究显示，在农村社区环境中的结果与以前在诊所中看到的结果相似。
Objective:Examine the relationship between colonization withStaphylococcus aureusin the community and symptomatic infection in two cohorts of Iowans.Design:Case series within cohort study.Participants:Rural Iowans selected from the Keokuk Rural Health Study, the Agricultural Health Study, and the Iowa Voter Registry.Methods:Longitudinal study within established cohorts evaluating documentedS. aureusinfections with samples available for molecular typing.Results:We examined this relationship in two cohorts of Iowans with a combined 11 incident cases ofS. aureusSSTI, for which samples were available. Seven of the 11 individuals (63.6%) were colonized at baseline, in the nose (3/7, 42.9%), or in both the nose and throat (57.1%). All seven cases had matching sequence types between colonization and infection isolates.Conclusions:Staphylococcus aureuscauses millions of skin and soft tissue infections yearly. Although colonization withS. aureusis a frequent antecedent to infection, many studies investigating the link between colonization and infection have taken place in a clinical setting, particularly in urban hospitals. Our study has shown similar results in a rural community setting to those previously seen in clinics.