Characterization of the angular memory effect of scattered light in biological tissues
Characterization of the angular memory effect of scattered light in biological tissues
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DOI：
10.1364/oe.23.013505
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发表时间：
2015-05-18
期刊：
影响因子：
3.8
通讯作者：
Gigan, Sylvain
中科院分区：
文献类型：
--
作者：
Schott, Sam;Bertolotti, Jacopo;Gigan, Sylvain
高分辨率光学显微镜在神经科学中是必不可少的，但在生物组织中存在散射，赠款进入大脑表层。最近开发的技术通过利用透射光中的角度相关性来使用散射光子进行成像，并且可能增加成像深度。但是这些相关性（“角度记忆效应”）的范围非常短，理论上应该只存在于散射介质的后面而不是内部。从对神经组织的测量和补充模拟，我们发现，生物组织中的强前向散射可以增强记忆效应范围，因此可能的视场比类似于1 mm厚的组织层的各向同性散射多一个数量级。(C)2015美国光学学会
High resolution optical microscopy is essential in neuroscience but suffers from scattering in biological tissues and therefore grants access to superficial brain layers only. Recently developed techniques use scattered photons for imaging by exploiting angular correlations in transmitted light and could potentially increase imaging depths. But those correlations ('angular memory effect') are of a very short range and should theoretically be only present behind and not inside scattering media. From measurements on neural tissues and complementary simulations, we find that strong forward scattering in biological tissues can enhance the memory effect range and thus the possible field-of-view by more than an order of magnitude compared to isotropic scattering for similar to 1 mm thick tissue layers. (C) 2015 Optical Society of America