Pregabalin in the treatment of inferior alveolar nerve paraesthesia following overfilling of endodontic sealer.
Pregabalin in the treatment of inferior alveolar nerve paraesthesia following overfilling of endodontic sealer.
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DOI：
10.4317/jced.51420
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发表时间：
2014-04
影响因子：
--
通讯作者：
Segura-Egea JJ
中科院分区：
文献类型：
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作者：
Alonso-Ezpeleta O;Martín PJ;López-López J;Castellanos-Cosano L;Martín-González J;Segura-Egea JJ
摘要本文报告一个使用强的松及普瑞巴林治疗下颌管内牙髓炎后，出现口面疼痛及下牙槽神经感觉异常的病例。一位36岁的女性接受根管治疗的下颌第二右前磨牙。术后曲面断层片显示下颌管中存在不透射线的管壁。诊断为根管扩张后继发的IAN损伤。决定非手术治疗，包括：1 mg/kg/天泼尼松2次/天，每日1次方案，和150 mg/天普瑞巴林，每日2次，通过定期随访监测进展。事件发生六周后，症状和体征消失了。感觉异常的完全解决和疼痛的控制表明，非手术方法，联合泼尼松和GABA类似物普瑞巴林，是一个很好的选择，在管理后的IAN损伤牙髓炎挤压。 关键词：牙髓病学，下牙槽神经，神经性疼痛，口面疼痛，感觉异常，普瑞巴林。
A case of orofacial pain and inferior alveolar nerve (IAN) paraesthesia after extrusion of endodontic sealer within the mandibular canal treated with prednisone and pregabalin is described. A 36-year-old woman underwent root canal treatment of the mandibular second right premolar tooth. Post-operative panoramic radiograph revealed the presence of radiopaque canal sealer in the mandibular canal. Damage to IAN consecutive to extrusion of endodontic sealer was diagnosed. Non-surgical management was decided, including: 1 mg/kg/day prednisone 2 times/day, once-daily regimen, and 150 mg/day pregabalin, two doses per day, monitoring the progress with periodic follow-up visits. Six weeks after the incident the signs and symptoms were gone. The complete resolution of paraesthesia and the control of pain achieved suggest that a non-surgical approach, combining prednisone and the GABA analogue pregabalin, is a good option in the management of the IAN damage subsequent to endodontic sealer extrusion. Key words:Endodontics, inferior alveolar nerve, neuropathic pain, orofacial pain, paraesthesia, pregabalin.