Properties of the Sockeye Salmon Virus (Oregon Strain)∗
Properties of the Sockeye Salmon Virus (Oregon Strain)∗
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红鲑鱼病毒（俄勒冈株）的特性
DOI：
10.3181/00379727-130-33719
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发表时间：
1969
影响因子：
--
通讯作者：
K. Pilcher
中科院分区：
文献类型：
--
作者：
W. Wingfield;J. Fryer;K. Pilcher
摘要已确定了红鲑鱼病毒的几个重要特征。它在红鲑鱼细胞的培养中大量复制，产生特有的细胞病变效应。产生的大多数新病毒被释放到培养液中。通过膜过滤估计其颗粒大小在110-165mμ之间。病毒复制速率在13~18℃范围内最大，在23℃时没有复制，但宿主细胞在该温度下生长良好。乙醚破坏了病毒的感染性，表明存在必需的脂类。该试剂对5-溴脱氧尿苷抑制的抗性提供了其核酸为RNA的推定证据。
Summary Several important characteristics of the sockeye salmon virus have been determined. It replicates abundantly in cultures of sockeye salmon cells, producing characteristic cytopathic effects. Most of the new virus produced is released into the culture fluid. The particle size was estimated by membrane filtration to be in the range of 110-165 mμ. The maximum rate of virus replication was found in the temperature range from 13 to 18°, and no replication occurred at 23°, although host cells grew well at that temperature. Virus infectivity was destroyed by ether, indicating the presence of essential lipids. Resistance of the agent to inhibition by 5-bromodeoxyuridine offers presumptive evidence that its nucleic acid is RNA.