An experimental analysis of the development of the spinal column. V. Reactivity of chick somites
An experimental analysis of the development of the spinal column. V. Reactivity of chick somites
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脊柱发育的实验分析。
DOI：
10.1002/jez.1401320303
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发表时间：
1956
影响因子：
--
通讯作者：
H. Holtzer
中科院分区：
文献类型：
--
作者：
G. Avery;M. Chow;H. Holtzer
本实验的主要目的是探讨脊索在椎体软骨形成中的作用。在火蜥蜴身上定义这种关系的努力产生了相互矛盾的结果。Kitcher(‘49)报告说，脊索切除后，尾骨胚胎中的脊椎成分未能发育。基本上，Holtzer(‘52a)的相同操作导致了脊索对于椎骨软骨的形成是不可缺少的结论。同样，在再生的蜥蜴幼体尾巴中，脊椎软骨生成没有受到影响，尽管脊索没有再生(Holtzer，Holtzer和Avery，‘55)。脊索在雏鸡脊椎软骨形成中的作用也是不确定的。Williams(‘42)指出，鸡的脊索在中枢的形成中只起到机械作用。在缺少脊索的躯干组织的绒毛膜尿囊移植图中，Williams显示了脊髓运动表面下的软骨结构，类似于脊索切除后在火蜥蜴中发现的椎体样结构(比较图3)。威廉姆斯13岁，‘42
The primary purpose of the experitments presented here is to explore the contribution of the notochord to vertebral chondrogenesis. Efforts to define this relationship in the salamander have produced conflicting results. Kitchen ('49) reported that vertebral elements failed to develop following notochordectomy in the urodele embryo. Essentially the same operation by Holtzer ('52a) led to the conclusion that the notochord was dispensable to the formation of vertebral cartilage. Likewise, in the regenerated larval salamander tail, vertebral chondrogenesis mas unimpecled though the notochord did not regenerate (Holtzer, Holtzer and Avery,'55). The role of the notochord in vertebral chondrogenesis in the chick is also uncertain. Williams ('42) stated that the chick notochord plays only a mechanical role in'the formation of the centra. In a figure of a chorio-allantoic graft of trunk tissues lacking a notochord, Williams indicates a cartilaginous structure beneath the motor surface of the spinal cord similar to the centrum-like formations found in the salamander following notochordectomy (compare fig. 13 in Williams,'42