The clinical features of Tourette's disorder with obsessive-compulsive symptoms
The clinical features of Tourette's disorder with obsessive-compulsive symptoms
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DOI：
10.1111/j.1440-1819.1996.tb02740.x
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发表时间：
1996-08-01
影响因子：
11.9
通讯作者：
Ikawa, G
中科院分区：
文献类型：
--
作者：
Iida, J;Sakiyama, S;Ikawa, G
对23例抽动秽语障碍患者（13例有强迫症状，10例无强迫症状）进行了对照研究。与无强迫症的抽动秽语障碍患者相比，发现患有强迫症的患者的特征在于（i）更高的易变脾气发生率，（ii）更高的强迫性联系发生率，（iii）更高的围产期疾病和脑波异常发生率，（iv）使用严重程度量表评定的更高的严重程度，以及（v）更高的并发症患病率，特别是发育障碍。在伴有OCS的抽动秽语障碍的受试者中，约有一半在关系开始时发展为OCS。这些研究结果表明，与无强迫症的抽动秽语障碍相比，强迫症伴发的抽动秽语障碍与器质性脑障碍的相关性更强，与抽动障碍的部位无关。
Twenty-three patients with Tourette's disorder (13 with obsessive-compulsive symptoms [OCS] and 10 without) were comparatively investigated. In contrast to OCS-free Tourette's disorder patients, those with OCS were found to be characterized by (i) a higher incidence of volatile temper, (ii) a higher incidence of compulsive ties, (iii) a higher incidence of perinatal disorders and brain wave abnormalities, (iv) a higher severity as rated using the Severity Scale, and (v) a higher prevalence of complications, especially of developmental disorders. Of the subjects with OCS-accompanied Tourette's disorder, approximately half had developed OCS by the onset of ties. These findings suggest the likelihood that OCS-accompanied Tourette's disorder is more strongly associated with organic cerebral disorders, independently of sites of tic disorders, than is OCS-free Tourette's disorder.