GENOTYPE and GENODIVE: two programs for the analysis of genetic diversity of asexual organisms

GENOTYPE and GENODIVE: two programs for the analysis of genetic diversity of asexual organisms
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DOI:
10.1111/j.1471-8286.2004.00770.x
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发表时间:
2004-12-01
期刊:
MOLECULAR ECOLOGY NOTES
影响因子:
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通讯作者:
Van Tienderen, PH
Van Tienderen, PH
中科院分区:
其他
文献类型:
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作者:
Meirmans, PG;Van Tienderen, PH

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利用分子标记研究无性生物的多样性涉及。克隆谱系的个体分配和克隆多样性分析。可以使用距离矩阵结合用户指定的阈值进行分配,该阈值定义为被认为属于同一克隆谱系的两个个体之间的最大距离。克隆多样性分析需要检验种群间多样性和克隆组成的差异。我们开发了两个程序,GENOTYPE和GENODIVE来分析无性繁殖生物的克隆多样性。此外,GENOTYPE还可用于检测有性生物研究中的基因分型错误。
Investigating diversity in asexual organisms using molecular markers involves.the assignment of individuals to clonal lineages and the subsequent analysis of clonal diversity. Assignment is possible using a distance matrix in combination with a user-specified threshold, defined as the maximum distance between two individuals that are considered to belong to the same clonal lineage. Analysis of clonal diversity requires tests for differences in diversity and clonal composition between populations. We developed two programs, GENOTYPE and GENODIVE for such analyses of clonal diversity in asexually reproducing organisms. Additionally, GENOTYPE can be used for detecting genotyping errors in studies of sexual organisms.