MR CHARACTERIZATION OF SUSPICIOUS BREAST-LESIONS WITH A GADOLINIUM-ENHANCED TURBOFLASH SUBTRACTION TECHNIQUE
MR CHARACTERIZATION OF SUSPICIOUS BREAST-LESIONS WITH A GADOLINIUM-ENHANCED TURBOFLASH SUBTRACTION TECHNIQUE
复制标题
DOI：
10.1148/radiology.193.3.7972823
复制
发表时间：
1994-12-01
期刊：
影响因子：
19.7
通讯作者：
RUYS, SHJ
中科院分区：
文献类型：
--
作者：
BOETES, C;BARENTSZ, JO;RUYS, SHJ
目得：评估钆增强动态磁共振（MR）成像与涡轮快速低角度拍摄（Turbo-FLASH）技术在乳腺良恶性病变的鉴别中的实用性。材料和方法：对比剂增强MR图像以2.3秒的间隔获得2分钟。在获得前四个图像后，在10秒内静脉注射造影剂。主动脉显影后11.5秒内增强的病变被认为是恶性的。在主动脉后增强超过11.5秒的病变被认为是良性的。离心增强模式被认为是良性病变的标志。结果：87个病变进行了评估。组织学检查显示65例为恶性，22例为良性。结论：钆增强TurboFLASH对乳腺良恶性病变的诊断敏感性为95%，特异性为86%，总的诊断准确率为93%。
PURPOSE: To assess the utility of gadolinium-enhanced dynamic magnetic resonance (MR) imaging with turbo fast low-angle shot (Turbo-FLASH) technique in the differentiation of benign from malignant lesions of the breast.MATERIALS AND METHODS: Contrast material-enhanced MR images were obtained at intervals of 2.3 seconds for 2 minutes. After the first four images were obtained, contrast medium was intravenously injected within 10 seconds. Lesions that enhanced within 11.5 seconds after the aorta opacified were regarded as malignant. Lesions that enhanced more than 11.5 seconds after the aorta were regarded as benign. A centrifugal pattern of enhancement was regarded as a sign that a lesion was benign.RESULTS: Eighty-seven lesions were evaluated. Histologic examination showed 65 lesions were malignant and 22 were benign. Gadolinium-enhanced TurboFLASH imaging had a sensitivity of 95%, a specificity of 86%, and an overall accuracy of 93% in differentiating benign from malignant lesions.CONCLUSION: Gadolinium-enhanced TurboFLASH imaging is a valuable method in the examination of breast lesions suspected of being malignant.