Multipoint molecular recognition of amino acids and biogenic amines by ureidocalix[5]arene receptors
Multipoint molecular recognition of amino acids and biogenic amines by ureidocalix[5]arene receptors
复制标题
DOI：
10.1021/ol034093b
复制
发表时间：
2003-04-03
期刊：
影响因子：
5.2
通讯作者：
Pisagatti, I
中科院分区：
文献类型：
--
作者：
Ballistreri, FP;Notti, A;Pisagatti, I
[图]对叔丁基杯[5]芳烃呈固定锥形构象，在上缘具有尿素功能，是omega-氨基酸和生物胺的高效非生物受体，它们与链的一端结合在pi-碱腔内（一级识别位点），另一端被二级氢键供体/受体结合位点抓住。
[GRAPHIC]p-tert-Butylcalix[5]arenes in a fixed cone conformation, endowed with a urea functionality at the upper rim, behave as remarkably efficient abiotic receptors of omega-amino acids and biogenic amines, which are bound with one end of the chain within the pi-basic cavity (primary recognition site) and the other grasped by the secondary hydrogen bonding donor/acceptor binding site.