Aberrant methylation of genes in stool samples as diagnostic biomarkers for colorectal cancer or adenomas: A meta-analysis

Aberrant methylation of genes in stool samples as diagnostic biomarkers for colorectal cancer or adenomas: A meta-analysis
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粪便样本中基因的异常甲基化作为结直肠癌或腺瘤的诊断生物标志物:荟萃分析

DOI:
10.1111/j.1742-1241.2011.02800.x
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发表时间:
2011-12-01
影响因子:
2.6
通讯作者:
Wang, J. -P.
Wang, J. -P.
中科院分区:
医学4区
文献类型:
--
作者:
Luo, Y. -X.;Chen, D. -K.;Wang, J. -P.

文献摘要

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工作背景:粪便样本中越来越多的高甲基化基因已被报道为检测结直肠癌(CRC)或腺瘤的生物标志物。我们的目的是全面审查和比较使用这些生物标志物检测结直肠肿瘤的可行性的证据。
Background: An increasing number of hypermethylated genes in stool samples have been reported as biomarkers for the detection of colorectal cancer (CRC) or adenomas. We aimed to comprehensively review and compare the evidence for feasibility of using these biomarkers for the detection of colorectal neoplasia.